On the automorphisms of moduli spaces of curves

In the last years the biregular automorphisms of the Deligne-Mumford's and Hassett's compactifications of the moduli space of n-pointed genus g smooth curves have been extensively studied by A. Bruno and the authors. In this paper we give a survey of these recent results and extend our techniques to some moduli spaces appearing as intermediate steps of the Kapranov's and Keel's realizations of $\bar{M}_{0,n}$, and to the degenerations of Hassett's spaces obtained by allowing zero weights.Comment: 15 pages. The material of version 1 has been reorganized and expanded in this paper and in arXiv:1307.6828 on automorphisms of Hassett's moduli space

Accounting Standards, Information Flow, and Firm Investment Behavior

We present a description of two different accounting regimes that govern reporting practice in most developed countries. 'One-book' countries, e.g. Germany, use their tax books as the basis for financial reporting and 'two-book' countries, e.g. the United States, keep the books largely separate. We derive a structural model and formalize a testable implication of our discussion: firms in one-book countries may be reluctant to claim some tax benefits if reductions in taxable income may be misinterpreted by financial market participants as signals of lower profitability. Econometric estimates suggest that accounting regime differences play an important role in describing domestic investment patterns both within and across countries.

Tax Reforms and Investment: A Cross-Country Comparison

We use firm-level panel data to explore the extent to which fixed investment responds to tax reforms in 14 OECD countries. Previous studies have often found that investment does not respond to changes in the marginal cost of investment. We identify some of the factors responsible for this finding and employ an estimation procedure that sidesteps the most important of them. In so doing, we find evidence of statistically and economically significant investment responses to tax changes in 12 of the 14 countries.

An extremal effective survey about extremal effective cycles in moduli spaces of curves

We survey recent developments and open problems about extremal effective divisors and higher codimension cycles in moduli spaces of curves.Comment: Submitted to the Proceedings of the Abel Symposium 2017. Comments are welcom

Stability conditions and positivity of invariants of fibrations

We study three methods that prove the positivity of a natural numerical invariant associated to $1-$parameter families of polarized varieties. All these methods involve different stability conditions. In dimension 2 we prove that there is a natural connection between them, related to a yet another stability condition, the linear stability. Finally we make some speculations and prove new results in higher dimension.Comment: Final version, to appear in the Springer volume dedicated to Klaus Hulek on the occasion of his 60-th birthda

BdlA, DipA and Induced Dispersion Contribute to Acute Virulence and Chronic Persistence of Pseudomonas aeruginosa

The human pathogen Pseudomonas aeruginosa is capable of causing both acute and chronic infections. Differences in virulence are attributable to the mode of growth: bacteria growing planktonically cause acute infections, while bacteria growing in matrix-enclosed aggregates known as biofilms are associated with chronic, persistent infections. While the contribution of the planktonic and biofilm modes of growth to virulence is now widely accepted, little is known about the role of dispersion in virulence, the active process by which biofilm bacteria switch back to the planktonic mode of growth. Here, we demonstrate that P. aeruginosa dispersed cells display a virulence phenotype distinct from those of planktonic and biofilm cells. While the highest activity of cytotoxic and degradative enzymes capable of breaking down polymeric matrix components was detected in supernatants of planktonic cells, the enzymatic activity of dispersed cell supernatants was similar to that of biofilm supernatants. Supernatants of non-dispersing Delta bdlA biofilms were characterized by a lack of many of the degradative activities. Expression of genes contributing to the virulence of P. aeruginosa was nearly 30-fold reduced in biofilm cells relative to planktonic cells. Gene expression analysis indicated dispersed cells, while dispersing from a biofilm and returning to the single cell lifestyle, to be distinct from both biofilm and planktonic cells, with virulence transcript levels being reduced up to 150-fold compared to planktonic cells. In contrast, virulence gene transcript levels were significantly increased in non-dispersing Delta bdlA and Delta dipA biofilms compared to wild-type planktonic cells. Despite this, bdlA and dipA inactivation, resulting in an inability to disperse in vitro, correlated with reduced pathogenicity and competitiveness in cross-phylum acute virulence models. In contrast, bdlA inactivation rendered P. aeruginosa more persistent upon chronic colonization of the murine lung, overall indicating that dispersion may contribute to both acute and chronic infections

Characteristics of Fibromyalgia Independently Predict Poorer Long‐Term Analgesic Outcomes Following Total Knee and Hip Arthroplasty

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111198/1/art39051.pd

Restoring Rivers One Reach at a Time: Results from a Survey of U.S. River Restoration Practitioners

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72915/1/j.1526-100X.2007.00244.x.pd

Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk

lung cancer ris